Anziani Associazioni Autori Biologia Chirurgia estetica Clinica chirurgica Clinica medica Clinica ortopedica Dermatologia Diagnostica Farmaci Fisiologia Grandi argomenti Igiene Odontoiatria Osteoporosi Pediatria Sessuologia Tumori
TUMORS: antineoplastic drugs
Antonino Raitano
Some antineoplastic drugs give the best results on tumour cells, by different action ways, that are on ipoxic or in acidosis or in glucose deficit.
These drugs, called " bioriduced alkilants agents", for example mytomicin C, are more toxic in ipoxic tumoural cells (up to 10 times) and in high doses of drug.
In solid tumours this choice is also possible by a special technique, called " stop-flow", with a short and controlled loco-regional treatment.
This is a useful alternative to a systemic therapy iin selective, non responders, patients.
Nowadays it is important a multi-modulary therapy in the cancer's strategic treatment, by a better target control (tumour), by reducing drug secondary effects and mixing rationally different therapeutic choices.
Daniele Franchini